Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Biological Context
Subcellular Location: Cell membrane (Single-pass type III membrane protein); Endomembrane system (Single-pass type III membrane protein)
Tissue Specificity: Expressed in mature B-cells, but not in T-cells or monocytes
Disease Association: [A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2]
Product Specifications
Mouse anti-Human sapiens (Human) TNFRSF17 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications. Explore more TNF Family proteins →
Catalog number: BCREC-000212MA.

