About BioCrest Sci

A Recombinant Protein Supplier and Custom Protein Production Partner

BioCrest Sci is a recombinant protein supplier and protein and antibody contract research organization serving pharmaceutical, biotechnology, diagnostic, and academic laboratories worldwide.

Our work connects ready-to-order research reagents with custom development. Researchers can search a broad recombinant protein catalog or work directly with our scientific team on protein expression, purification, characterization, antibody development, and difficult targets that standard catalogs may not cover.

Across our catalog and custom development programs, BioCrest Sci supports more than 12,000 recombinant proteins and 2,000 antibodies. More than 6,000 recombinant protein products are currently searchable in our online catalog, with additional targets, constructs, formats, and production scales available through custom projects.

Primary calls to action

BioCrest Sci at a Glance

  • 12,000+ recombinant proteins across catalog and custom development work
  • 6,000+ recombinant proteins online and searchable by target and product specifications
  • 2,000+ antibodies across catalog and custom programs
  • 8,000+ completed projects supporting research and development needs
  • Multiple expression systems including bacterial, mammalian, insect, yeast, and cell-free platforms
  • Microgram-to-kilogram production options for research and scale-up requirements
  • Researchers served in 50+ countries

Recombinant Proteins for Research and Drug Discovery

Recombinant proteins are the center of BioCrest Sci’s product and service portfolio. We provide proteins for immunology, oncology, neuroscience, infectious-disease research, cell biology, assay development, antibody discovery, diagnostics, and drug-target studies.

Our catalog includes:

  • Cytokines, chemokines, and growth factors
  • Interleukins and receptors
  • CD proteins and immune-checkpoint targets
  • Enzymes and kinases
  • Viral antigens
  • Active proteins
  • Avi-tagged and biotinylated proteins
  • Native and recombinant antigens
  • Full-length and multi-pass transmembrane proteins

Products may be available across different species, expression systems, sequence ranges, tags, purity levels, formulations, and activity specifications. Researchers should review each product page and lot-specific documentation to confirm that a protein matches the intended assay.

Related links

Custom Protein Expression and Production

When a suitable catalog protein is unavailable, BioCrest Sci provides custom recombinant protein production from sequence design through purified protein and quality-control documentation.

Our team can support:

  • Sequence and construct review
  • Gene synthesis and codon optimization
  • Vector construction and expression screening
  • Soluble expression and inclusion-body recovery
  • Process optimization and scale-up
  • Affinity, ion-exchange, size-exclusion, and other purification strategies
  • Tag removal, buffer exchange, and endotoxin reduction
  • SDS-PAGE, Western blot, concentration, endotoxin, and optional functional testing

Available expression platforms include:

Bacterial expression

E. coli expression is often suitable for antigens, enzymes, protein domains, and other targets that do not require complex mammalian post-translational modifications.

Explore Bacterial Protein Expression

Mammalian expression

HEK293 and CHO systems support proteins that require mammalian folding, secretion, disulfide-bond formation, or glycosylation.

Explore Mammalian Protein Expression

Insect, yeast, and cell-free expression

These systems provide additional options for complex, toxic, difficult-to-express, or scale-sensitive proteins.

Specialized Expertise in Transmembrane Proteins

Full-length transmembrane proteins can be difficult to express, stabilize, purify, and present in a biologically relevant format. BioCrest Sci supports GPCRs, ion channels, transporters, and other membrane-associated targets using several platform options:

  • Detergent-solubilized proteins
  • Synthetic nanodiscs
  • Virus-like particles (VLPs)
  • Exosome-based presentation
  • Membrane nanoparticles
  • Cell-free expression

The appropriate format depends on the target and downstream application, including immunization, antibody screening, binding studies, drug discovery, assay development, and structural research.

Explore Transmembrane Protein Expression

Antibodies and Custom Antibody Development

BioCrest Sci also provides catalog antibodies and custom antibody programs that connect antigen preparation with screening, engineering, and validation.

Capabilities include:

  • Monoclonal and polyclonal antibody development
  • Recombinant antibody production
  • Neutralizing-antibody programs
  • Nanobody and VHH development
  • Single B-cell screening
  • Phage-display screening
  • Antibody humanization
  • Antibody conjugation and engineering

This integrated approach is useful when a project requires coordinated antigen design, recombinant protein production, antibody generation, and downstream binding or functional validation.

Explore Custom Antibody Production

Quality You Can Review

Reliable research reagents require more than a catalog number. BioCrest Sci emphasizes product- and lot-specific evidence so researchers can evaluate whether a reagent is appropriate for their experiment.

Depending on the product or project, documentation may include:

  • SDS-PAGE purity data
  • Western blot confirmation
  • Protein concentration and formulation
  • Endotoxin results
  • Sequence, construct, and tag information
  • Expression-system details
  • Certificate of Analysis
  • Optional binding, enzyme, or cell-based activity data
  • Raw instrument files for custom projects when included in the project scope

Specifications differ by product and project. Researchers should confirm the current product page, Certificate of Analysis, and quoted project deliverables before ordering.

A Scientist-to-Scientist Working Model

BioCrest Sci approaches custom development as a scientific collaboration. Our team reviews feasibility before a project begins, recommends an appropriate expression system and construct strategy, and communicates technical risks that may affect solubility, yield, folding, activity, or scale-up.

Our working principles are straightforward:

  1. Assess feasibility early. We evaluate the sequence, construct, expression system, purification plan, and downstream application before recommending a route.
  2. Match the protein to the experiment. Purity, endotoxin, activity, tag, species, and formulation requirements should reflect the actual assay.
  3. Share usable evidence. Product and project decisions should be supported by relevant QC data and clear documentation.
  4. Communicate problems directly. Difficult biology can create unexpected results. We explain risks and discuss alternatives rather than treating every target as identical.

Supporting Researchers Worldwide

BioCrest Sci serves academic, biotechnology, pharmaceutical, and diagnostic laboratories in more than 50 countries. Researchers can order catalog products or request technical review for custom constructs, bulk quantities, specialized formulations, additional QC, and difficult-to-source targets.

Talk With Our Scientific Team

Whether you need a catalog recombinant protein, a custom construct, a low-endotoxin format, a membrane-protein solution, or an integrated protein-and-antibody program, our team can help evaluate the most practical route.

For research use only. Product availability, specifications, documentation, lead times, and permitted uses should be confirmed on the relevant product page or quotation.

Shopping Cart
Scroll to Top