Recombinant Cytokines, Chemokines & Growth Factors
BioCrest Sci supplies recombinant cytokines, chemokines, growth factors, and receptors for immunology, oncology, inflammation, stem cell, cell culture, and drug discovery research. The portfolio covers interleukins, interferons, TNF superfamily members, colony-stimulating factors, CCL/CXCL chemokines, and major growth-factor families in multiple species, expression systems, and tag formats.
Explore Major Protein Families
Interleukins and Receptors
Explore IL-1, IL-2, IL-6, IL-10, IL-12, IL-17 and related families for T-cell, B-cell, NK-cell, inflammatory, and immune-signaling research.
Chemokines and Receptors
CC, CXC, XC, and CX3C chemokines support chemotaxis, leukocyte migration, inflammation, tumor-microenvironment, and receptor-binding studies.
Growth Factors and Receptors
EGF, FGF, VEGF, IGF, TGF-β, BMP, activin, and neurotrophin families are widely used in cell culture, angiogenesis, regenerative medicine, organoid, and developmental biology research.
Interferons
IFN-α, IFN-β, IFN-γ, IFN-λ and associated receptors support antiviral immunity, innate immune signaling, and immuno-oncology studies.
TNF Family Proteins
TNF-α, TRAIL, RANKL, CD40L, FasL, and related receptors support apoptosis, inflammation, immune regulation, and therapeutic target research.
Colony-Stimulating Factors
G-CSF, GM-CSF, M-CSF and their receptors are used in hematopoiesis, myeloid-cell differentiation, immune-cell culture, and cytokine signaling research.
Research Applications
- Immunology and immuno-oncology: immune-cell activation, differentiation, expansion, and signaling
- Cell and organoid culture: maintenance, proliferation, and lineage-specific differentiation
- Inflammation and autoimmune research: cytokine pathways, receptors, and therapeutic targets
- Drug discovery: receptor binding, antibody screening, potency assays, and pathway studies
- Migration and angiogenesis: chemotaxis, endothelial biology, and tumor-microenvironment research
How to Choose a Recombinant Cytokine
Match the species, sequence, expression system, tag, carrier protein, formulation, purity, endotoxin level, and activity validation to the experiment. Active proteins are appropriate when a functional response is required, while receptor-binding or antibody-screening assays may prioritize tag format and immobilization strategy. Review individual datasheets because activity and quality-control methods are product-specific.
Why BioCrest Sci
- Multiple species and expression systems, including E. coli, yeast, insect, and mammalian cells
- His-tagged, Fc-tagged, Avi-tagged, biotinylated, and tag-free options
- Active-protein formats with product-specific activity data where stated
- In-stock and ready-to-ship catalog options without fixed dispatch-time claims
- Custom Protein Expression Services for targets or formats not covered by the catalog
Frequently Asked Questions
What is the difference between cytokines and chemokines?
Cytokines are signaling proteins that regulate immune and cellular responses. Chemokines are a cytokine subgroup best known for directing cell migration through concentration gradients.
Which expression system should I choose?
E. coli can be suitable for non-glycosylated proteins, while mammalian expression may be preferred when native-like folding and glycosylation are important. The best choice depends on the assay and target biology.
Are all catalog cytokines biologically active?
No. Activity is product-specific. Choose an active protein when functional validation is required and verify the assay information on the individual product page.
Need help selecting a protein? Contact sales@biocrestsci.com.