Recombinant Viral Antigens for Vaccine, Diagnostic & Serology Research
BioCrest Sci supplies recombinant viral antigens for vaccine research, serological assay development, antibody screening, diagnostic development, and antiviral studies. The catalog includes structural and non-structural proteins from respiratory, blood-borne, herpes, and emerging viruses in multiple expression systems and tag formats.
Viral Antigen Collections
Coronavirus Antigens
SARS-CoV-2 Spike, S1, RBD, Nucleocapsid, and proteins from SARS, MERS, and seasonal coronaviruses support serology, neutralization, antibody characterization, and vaccine research. Browse Coronavirus Antigens →
Influenza Antigens
Hemagglutinin, neuraminidase, nucleoprotein, matrix, and other influenza proteins are available for strain-specific assay development, antibody screening, and vaccine research. Browse Influenza Antigens →
Hepatitis Virus Antigens
HBV surface and core antigens, HCV proteins, and related viral targets support diagnostic assay development, serology, immunogenicity studies, and antiviral research.
Herpesvirus and HSV Antigens
Herpesvirus proteins include selected antigens from HSV-1, HSV-2, varicella-zoster virus, cytomegalovirus, and other human herpesviruses. Available targets include envelope glycoproteins and tegument proteins used in serology, antibody screening, and vaccine research.
- HSV-2 Envelope Glycoprotein E (gE)
- HSV-2 Tegument Protein VP22 (UL49)
- Varicella-Zoster Virus Envelope Glycoprotein E
Other Viral Antigens
The broader collection includes proteins from SIV, Ebola virus, HPV, Lassa virus, rotavirus, poxviruses, and other human, animal, and emerging viruses.
Research Applications
- ELISA, lateral-flow, and serological assay development
- Vaccine antigen characterization and immunogenicity research
- Neutralizing and binding-antibody screening
- Reference standards and assay calibration
- Antiviral target and epidemiological research
How to Choose a Viral Antigen
Consider the virus species and strain, protein region, expression system, tag position, expected folding or glycosylation, and downstream assay. Mammalian expression may be useful for glycosylated envelope proteins, while bacterial expression may suit linear-epitope or screening applications. Review each product datasheet for sequence, purity, tag, and recommended use.
Frequently Asked Questions
Do you offer HSV antigens?
Yes. The catalog includes selected HSV-2 and other herpesvirus proteins. Use the product-specific sequence and strain information to confirm suitability for your assay.
Which viral antigen format is best for antibody screening?
The optimal format depends on whether the antibody recognizes a conformational or linear epitope. Expression system, protein boundaries, glycosylation, and tag orientation should all be considered.
Are all viral antigens biologically active?
No. Biological activity and validation are product-specific. Many viral antigens are intended for binding, serology, or immunoassay applications rather than functional activity assays.