Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody
Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody - Image 2
Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody - Image 3

Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody

Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody — ATP-dependent protein-folding chaperone for the eIF2 complex.

SKU: BCREC-000419MA Category:
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Product Specifications

Uniprot No.O75794
Target NamesCDC123
Species ReactivityMouse
ImmunogenRecombinant Human CDC123 protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG2b
ClonalityMonoclonal
ApplicationsELISA, WB, FC, ICC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

ATP-dependent protein-folding chaperone for the eIF2 complex. Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits.

Biological Context

Subcellular Location: Cytoplasm
Tissue Specificity: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis

Product Specifications

Mouse anti-Human sapiens (Human) CDC123 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity)

Subcellular Location

Cytoplasm

Tissue Specificity

Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis

Subunit

Interacts with the eIF2 complex gamma subunit EIF2S3 (via C-terminus); the interaction is direct (PubMed:35031321, PubMed:37507029). Interacts with the eIF2 complex alpha subunit EIF2S1 (PubMed:31836389, PubMed:35031321). Interacts with the eIF2 complex beta subunit EIF2S2 (PubMed:31836389, PubMed:35031321)

Gene: CDC123  |  Organism: Homo sapiens  |  Synonyms: Cell division cycle protein 123 homolog; HT-1080; PZ32
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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