Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody
Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody - Image 2

Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody

Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody — Implicated in endocytosis.

SKU: BCREC-000521MA Category:
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Product Specifications

Uniprot No.Q99961
Target NamesSH3GL1
Species ReactivityMouse
ImmunogenRecombinant Human SH3GL1 protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG1
ClonalityMonoclonal
ApplicationsELISA, WB, FC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles. May recruit other proteins to membranes with high curvature.

Biological Context

Subcellular Location: Cytoplasm; Early endosome membrane (Peripheral membrane protein); Cell projection, podosome
Tissue Specificity: Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus
Disease Association: [In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene]

Product Specifications

Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles (By similarity). May recruit other proteins to membranes with high curvature (By similarity)

Subcellular Location

Cytoplasm; Early endosome membrane (Peripheral membrane protein); Cell projection, podosome

Disease Association

[In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene]

Tissue Specificity

Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus

Subunit

Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP. Interacts with BIN2

Gene: SH3GL1  |  Organism: Homo sapiens  |  Synonyms: EEN fusion partner of MLL; Endophilin-2; Extra eleven-nineteen leukemia fusion gene protein; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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