Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Mammalian cell, C-terminal hFc1-tagged, 112.7 kDa, purity >90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
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Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active)

Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active) — recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000084 Categories: ,
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Product SKUBCACP-000084
Product DescriptionRecombinant Cynomolgus monkey Angiotensin-converting enzyme (ACE2) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 18-741aa. [Accession | A0A2K5X283].
Uniprot No.A0A2K5X283
Gene NamesACE2
PurityGreater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region18-741aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal hFc1-tagged
Molecular weight112.7 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized CD7 at 5 μg/ml can bind human SECTM1, the EC50 is 1.811-3.372 ng/ml.;Human CD7 protein hFc and Myc tag captured on COOH chip can bind Human SECTM1 protein hFc tag with an affinity constant of 1.84 nM as detected by LSPR Assay.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Biological Context

Subcellular Location: Apical cell membrane; Cell membrane (Single-pass type I membrane protein); Cell projection, cilium; Cytoplasm; Secreted

Product Specifications

Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 18-741aa, with C-terminal hFc1-tagged tag, molecular weight 112.7 kDa, purity Greater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Subcellular Location

Apical cell membrane; Cell membrane (Single-pass type I membrane protein); Cell projection, cilium; Cytoplasm; Secreted

Subunit

Homodimer. Interacts with the catalytically active form of TMPRSS2. Interacts with SLC6A19; this interaction is essential for expression and function of SLC6A19 in intestine. Interacts with ITGA5:ITGB1. Probably interacts (via endocytic sorting signal motif) with AP2M1; the interaction is inhibited by phosphorylation of Tyr-781. Interacts (via PDZ-binding motif) with NHERF1 (via PDZ domains); the interaction may enhance ACE2 membrane residence

Organism: Macaca fascicularis

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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