Recombinant Human Augurin(ECRG4), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 20.8kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Augurin(ECRG4), partial

Recombinant Human Augurin(ECRG4), partial — Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. Purity >85%.

SKU: BCRECP-000556 Category:
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Product Specifications

Product SkuBCRECP-000556
Product DescriptionRecombinant Human Augurin(ECRG4) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 71-132aa. [Accession | Q9H1Z8].
Uniprot No.Q9H1Z8
Gene NamesECRG4
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region71-132aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight20.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.

Biological Context

Subcellular Location: Secreted; Cytoplasm; Apical cell membrane
Tissue Specificity: Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level)

Product Specifications

Recombinant Human Augurin(ECRG4), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 71-132aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 20.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity)

Subcellular Location

Secreted; Cytoplasm; Apical cell membrane

Tissue Specificity

Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level)

Gene: ECRG4  |  Organism: Homo sapiens  |  Synonyms: Esophageal cancer-related gene 4 protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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