Function
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Biological Context
Subcellular Location: Secreted
Disease Association: Epilepsy, familial temporal lobe, 8 (ETL8) : A focal form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe. Seizures are usually accompanied by sensory symptoms, most often auditory in nature. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Galanin peptides (GAL), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 44-123aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 16.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
