Function
Serine protease required during eye development.
Biological Context
Tissue Specificity: Expressed neural retina, cornea, sclera and optic nerve
Disease Association: Microphthalmia, isolated, 6 (MCOP6) : A developmental ocular disorder characterized by small malformed eyes. Clinical features are extreme hyperopia due to short axial length with essentially normal anterior segment, steep corneal curvatures, shallow anterior chamber, thick lenses, and thickened scleral wall. Palpebral fissures appear narrow because of relatively deep-set eyes, visual acuity is mildly to moderately reduced, and anisometropic or strabismic amblyopia is common. The fundus of the eye shows crowded optical disks, tortuous vessels, and an abnormal foveal avascular zone. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Serine protease 56 (PRSS56) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-603aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 70.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Protease proteins →
