BioCrest Sci · Custom Antibody Production Service

BioCrest Sci

Custom Antibodies · Research · Diagnostics · Therapeutics

End‑to‑End Antibody Development · Multi‑platform Customization · Transparent Science

Scientist‑to‑Scientist

Antibody Customization Services

Select the service that matches your project needs. Each option leads to a dedicated service page with detailed workflows, timelines, and technical specifications.

Custom Monoclonal Antibody

3–6 months

High‑specificity antibodies from a single clone. Ideal for diagnostic development, flow cytometry, IHC, and long‑term reproducibility.

Diagnostics Flow IHC

Custom Polyclonal Antibody

2–4 months

Rapid generation of antibody populations recognizing multiple epitopes. Well‑suited for WB, ELISA, protein tracking, and exploratory studies.

WB ELISA Exploration

Custom Recombinant Antibody

4–10 weeks (after sequence)

Sequence‑defined, renewable antibodies with batch‑to‑batch consistency. Supports engineering, humanization, affinity maturation & scalable manufacturing.

Therapeutics Engineering

Custom Nanobody (VHH)

3–5 months

Single‑domain antibody fragments with small size and high stability. Perfect for intracellular targeting, structural biology, CAR‑T, and biosensors.

Imaging CAR Intracellular

Neutralizing Antibody

Function‑driven

Functionally validated antibodies that block biological activity — viral entry, receptor‑ligand interaction, cytokine signaling, or enzymatic inhibition.

Antiviral Blocking

Comparison of Antibody Production Platforms

Select the right platform based on your research needs.
Service TypeMain AdvantagesTypical TimelineBest‑Fit Applications
Polyclonal AntibodyFast and broad epitope recognition~2–4 monthsWB, ELISA, exploratory studies
Monoclonal AntibodySpecificity and reproducibility~3–6 monthsDiagnostics, flow cytometry, IHC
Recombinant AntibodySequence‑defined renewable reagent~1–3 months after sequenceTherapeutic and engineered antibody research
Nanobody (VHH)Small size and high stability~3–5 monthsImaging, intracellular targeting, CAR research
Neutralizing AntibodyFunctional biological inhibitionVariableAntiviral and blocking studies
📌 Actual timelines vary depending on antigen immunogenicity, screening complexity & validation requirements.

Antigen Types Supported

Recombinant proteins, peptides (including phosphorylated), membrane proteins, GPCRs, ion channels, viral/bacterial antigens, toxins, haptens, and more.

Recombinant proteins Phospho‑peptides Membrane proteins GPCRs Viral antigens Fusion proteins Cytokines Low immunogenicity targets

Our scientists assist with epitope selection, antigen design, and immunization optimization.

Screening & Validation Options

Customizable screening aligned with your intended application:

  • ELISA / MSD binding
  • Western blot
  • Flow cytometry
  • Immunofluorescence (IF/ICC)
  • Immunohistochemistry (IHC)
  • Neutralization assays
  • SPR / BLI affinity
  • Cell‑based functional assays
  • Pair screening for sandwich ELISA
📊 Antigen Integrity · Pre‑immunization QC & serum titer monitoring 🧪 Clone Stability · Monoclonal screening & contamination testing 📝 Sequence Verification · For recombinant antibodies + SDS‑PAGE, endotoxin, concentration QC 🎯 Application‑Specific Validation · Tailored to your downstream assay, not generic testing
💡 If a strategy is unlikely to succeed, we will tell you upfront and recommend an alternative approach.

Why Researchers Choose BioCrest

Multiple platforms — monoclonal, polyclonal, recombinant, nanobody, neutralizing all in one place
Difficult target expertise — membrane proteins, conformational epitopes, low‑immunogenicity antigens
Transparent communication — weekly updates, raw data access, honest feasibility assessment
Flexible project scope — from exploratory generation to engineered functional antibodies

Frequently Asked Questions

❓ Which antibody platform is best for my project?
Depends on your antigen, timeline, downstream application, and whether you need recombinant or functional antibodies. Our scientists offer free strategy consultation.
❓ Can you generate antibodies against membrane proteins / GPCRs?
Yes. Peptide immunization, recombinant extracellular domains, cell‑based immunization, and recombinant screening workflows are available.
❓ Do you offer antibody sequencing and recombinant recovery?
Yes. Integrated into monoclonal, nanobody, and recombinant antibody workflows.

Start Your Custom Antibody Project

Contact Our Scientists → No obligation · Scientist‑to‑scientist conversation
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