Recombinant Human Serpin H1 (SERPINH1), Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged, 50.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Serpin H1 (SERPINH1)

Recombinant Human Serpin H1 (SERPINH1) — Binds specifically to collagen. Purity >90%.

SKU: BCRECP-001619 Category:
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Product Specifications

Product SkuBCRECP-001619
Product DescriptionRecombinant Human Serpin H1 (SERPINH1) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 19-418aa. [Accession | P50454].
Uniprot No.P50454
Gene NamesSERPINH1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region19-418aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight50.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

Biological Context

Subcellular Location: Endoplasmic reticulum lumen
Disease Association: Osteogenesis imperfecta 10 (OI10) : A form of osteogenesis imperfecta, a disorder of bone formation characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Serpin H1 (SERPINH1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 19-418aa, with N-terminal 10xHis-tagged tag, molecular weight 50.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen

Subcellular Location

Endoplasmic reticulum lumen

Disease Association

Osteogenesis imperfecta 10 (OI10) : A form of osteogenesis imperfecta, a disorder of bone formation characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae. [The disease is caused by variants affecting the gene represented in this entry]

Gene: SERPINH1  |  Organism: Homo sapiens  |  Synonyms: 47 kDa heat shock protein; Arsenic-transactivated protein 3; Cell proliferation-inducing gene 14 protein; Collagen-binding protein; Rheumatoid arthritis-related antigen RA-A47
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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