Recombinant Rat Retinol-binding protein 4 (Rbp4)

Recombinant Rat Retinol-binding protein 4 (Rbp4) — Retinol-binding protein that mediates retinol transport in blood plasma. Purity >90%.

SKU: BCRECP-004238 Category:

Product Specifications

Product SkuBCRECP-004238
Product DescriptionRecombinant Rat Retinol-binding protein 4 (Rbp4) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 19-201aa. [Accession | P04916].
Uniprot No.P04916
Gene NamesRbp4
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region19-201aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-tagged
Molecular weight25.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Detected in blood plasma (at protein level)

Product Specifications

Recombinant Rat Retinol-binding protein 4 (Rbp4) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 19-201aa, with N-terminal 6xHis-tagged tag, molecular weight 25.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues (PubMed:4708098). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Detected in blood plasma (at protein level)

Subunit

Interacts with TTR (PubMed:4708098). Interaction with TTR prevents its loss by filtration through the kidney glomeruli (Probable). Interacts with STRA6 (By similarity)

Gene: Rbp4  |  Organism: Rattus norvegicus  |  Synonyms: Plasma retinol-binding protein

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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