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Recombinant Candida albicans Glycerol-3-phosphate dehydrogenase [NAD (+)] 2 (GPD2)

Recombinant Candida albicans Glycerol-3-phosphate dehydrogenase [NAD (+)] 2 (GPD2) — May catalyze the production and accumulation of glycerol during hyperosmotic stress conditions. Purity >85%.

SKU: BCRECP-002900 Categories: ,

Product Specifications

Product SkuBCRECP-002900
Product DescriptionRecombinant Candida albicans Glycerol-3-phosphate dehydrogenase [NAD (+)] 2 (GPD2) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 1-371aa. [Accession | Q59W33].
Uniprot No.Q59W33
Gene NamesGPD2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region1-371aa
SpeciesCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Tag InfoC-terminal 6xHis-tagged
Molecular weight42.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

May catalyze the production and accumulation of glycerol during hyperosmotic stress conditions. Glycerol acts as a osmoregulator that prevents loss of water and turgor of the cells. Mediates evasion of the host innate immune system by binding inhibitory components of the host alternative complement system, in a manner dependent on estrogen-induced inhibition of EBP1.

Biological Context

Subcellular Location: Secreted, cell wall; Secreted; Cytoplasm; Peroxisome

Product Specifications

Recombinant Candida albicans Glycerol-3-phosphate dehydrogenase [NAD (+)] 2 (GPD2) is a recombinant protein from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast), expressed in Yeast, covering amino acids 1-371aa, with C-terminal 6xHis-tagged tag, molecular weight 42.3kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

May catalyze the production and accumulation of glycerol during hyperosmotic stress conditions (By similarity). Glycerol acts as a osmoregulator that prevents loss of water and turgor of the cells (By similarity). Mediates evasion of the host innate immune system by binding inhibitory components of the host alternative complement system, in a manner dependent on estrogen-induced inhibition of EBP1 (PubMed:23204165, PubMed:34986357)

Subcellular Location

Secreted, cell wall; Secreted; Cytoplasm; Peroxisome

Subunit

Interacts with human CFH/complement factor H; the interaction is direct and enables the pathogen to evade the host innate immune system (PubMed:23204165). Interacts with human CFHR1/complement factor H-related protein 1; the interaction is direct (PubMed:23204165). Interacts with human PLG/plasminogen; the interaction is direct and provides active plasmin on the surface of fungal cells (PubMed:23204165)

Gene: GPD2  |  Organism: Candida albicans (strain SC5314 / ATCC MYA-2876)
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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