Recombinant Human Aldo-keto reductase family 1 member B10 (AKR1B10), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 63.0kDa, purity >90% as determined by SDS-PAGE.
,

Recombinant Human Aldo-keto reductase family 1 member B10 (AKR1B10)

Recombinant Human Aldo-keto reductase family 1 member B10 (AKR1B10) — Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Purity >90%.

SKU: BCRECP-000052 Categories: ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-000052
Product DescriptionRecombinant Human Aldo-keto reductase family 1 member B10 (AKR1B10) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-316aa. [Accession | O60218].
Uniprot No.O60218
Gene NamesAKR1B10
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-316aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight63.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls).

Biological Context

Subcellular Location: Lysosome; Secreted
Tissue Specificity: Found in many tissues. Highly expressed in small intestine, colon and adrenal gland
Pathway: Cofactor metabolism; retinol metabolism

Product Specifications

Recombinant Human Aldo-keto reductase family 1 member B10 (AKR1B10) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-316aa, with N-terminal GST-tagged tag, molecular weight 63.0kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols (PubMed:12732097, PubMed:18087047, PubMed:19013440, PubMed:19563777, PubMed:9565553). Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal (PubMed:12732097, PubMed:18087047). Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) (PubMed:19013440, PubMed:19563777). Displays no reductase activity towards glucose (PubMed:12732097)

Subcellular Location

Lysosome; Secreted

Tissue Specificity

Found in many tissues. Highly expressed in small intestine, colon and adrenal gland

Pathway

Cofactor metabolism; retinol metabolism

Gene: AKR1B10  |  Organism: Homo sapiens  |  Synonyms: ARL-1; Aldose reductase-like; Aldose reductase-related protein; Small intestine reductase
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top