Recombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 50.7kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1)

Recombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1) — Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. Purity >90%.

SKU: BCRECP-001516 Category:
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Product Specifications

Product SkuBCRECP-001516
Product DescriptionRecombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 1-305aa. [Accession | Q5JS13].
Uniprot No.Q5JS13
Gene NamesRALGPS1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-305aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight50.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for.

Biological Context

Subcellular Location: Cytoplasm; Cell membrane
Tissue Specificity: Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus

Product Specifications

Recombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-305aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 50.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for

Subcellular Location

Cytoplasm; Cell membrane

Tissue Specificity

Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus

Subunit

Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC

Gene: RALGPS1  |  Organism: Homo sapiens  |  Synonyms: Ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor 2; RalA exchange factor RalGPS1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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