Recombinant Human Sal-like protein 4 (SALL4), partial

Recombinant Human Sal-like protein 4 (SALL4), partial — recombinant protein from Homo sapiens (Human), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-001579 Category:

Product Specifications

Product SkuBCRECP-001579
Product DescriptionRecombinant Human Sal-like protein 4 (SALL4) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 954-1053aa+11R. [Accession | Q9UJQ4].
Uniprot No.Q9UJQ4
Gene NamesSALL4
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region954-1053aa+11R
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight16kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasDevelopmental Biology

Function

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.

Biological Context

Subcellular Location: Cytoplasm; Nucleus
Tissue Specificity: Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML)
Disease Association: Duane-radial ray syndrome (DRRS) : Disorder characterized by the association of forearm malformations with Duane retraction syndrome. [The disease is caused by variants affecting the gene represented in this entry] | IVIC syndrome (IVIC) : An autosomal dominant condition characterized by upper limbs anomalies (radial ray defects, carpal bones fusion), extraocular motor disturbances, congenital bilateral non-progressive mixed hearing loss. Other less consistent malformations include heart involvement, mild thrombocytopenia and leukocytosis (before age 50), shoulder girdle hypoplasia, imperforate anus, kidney malrotation or rectovaginal fistula. The IVIC syndrome is an allelic disorder of Duane-radial ray syndrome with a similar phenotype. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Sal-like protein 4 (SALL4), partial is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 954-1053aa+11R, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 16kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells

Subcellular Location

Cytoplasm; Nucleus

Disease Association

Duane-radial ray syndrome (DRRS) : Disorder characterized by the association of forearm malformations with Duane retraction syndrome. [The disease is caused by variants affecting the gene represented in this entry] | IVIC syndrome (IVIC) : An autosomal dominant condition characterized by upper limbs anomalies (radial ray defects, carpal bones fusion), extraocular motor disturbances, congenital bilateral non-progressive mixed hearing loss. Other less consistent malformations include heart involvement, mild thrombocytopenia and leukocytosis (before age 50), shoulder girdle hypoplasia, imperforate anus, kidney malrotation or rectovaginal fistula. The IVIC syndrome is an allelic disorder of Duane-radial ray syndrome with a similar phenotype. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML)

Subunit

Interacts with POU5F1/OCT4 (PubMed:23012367). Interacts with NANOG (By similarity). Interacts with BEND3 (PubMed:21914818). Interacts with NSD2 (via PHD-type zinc fingers 1, 2 and 3) (By similarity). Interacts with NRBP1 (PubMed:22510880)

Gene: SALL4  |  Organism: Homo sapiens  |  Synonyms: Zinc finger protein 797; Zinc finger protein SALL4
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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