Recombinant Human Transcription regulator protein BACH2 (BACH2), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 23.5kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Transcription regulator protein BACH2 (BACH2), partial

Recombinant Human Transcription regulator protein BACH2 (BACH2), partial — Transcriptional regulator that acts as a repressor or activator. Purity >85%.

SKU: BCRECP-000149 Category:
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Product Specifications

Product SkuBCRECP-000149
Product DescriptionRecombinant Human Transcription regulator protein BACH2 (BACH2) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 618-770aa. [Accession | Q9BYV9].
Uniprot No.Q9BYV9
Gene NamesBACH2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region618-770aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight23.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Transcriptional regulator that acts as a repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcription activation and repression by MAFK.

Biological Context

Subcellular Location: Cytoplasm; Nucleus
Tissue Specificity: B-cell specific
Disease Association: Immunodeficiency 60 and autoimmunity (IMD60) : An autosomal dominant primary immunologic disorder characterized by intestinal inflammation, recurrent sino-pulmonary infections, impaired lymphocyte maturation, and variably decreased immunoglobulin production. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Transcription regulator protein BACH2 (BACH2), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 618-770aa, with N-terminal 6xHis-tagged tag, molecular weight 23.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Transcriptional regulator that acts as a repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation (PubMed:28530713)

Subcellular Location

Cytoplasm; Nucleus

Disease Association

Immunodeficiency 60 and autoimmunity (IMD60) : An autosomal dominant primary immunologic disorder characterized by intestinal inflammation, recurrent sino-pulmonary infections, impaired lymphocyte maturation, and variably decreased immunoglobulin production. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

B-cell specific

Subunit

Homodimer; disulfide-linked (PubMed:22194330). Heterodimer of BACH2 and Maf-related transcription factors (By similarity)

Gene: BACH2  |  Organism: Homo sapiens  |  Synonyms: BTB and CNC homolog 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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