Recombinant Mouse Tyrosine-protein kinase Srms (Srms), Mus musculus (Mouse), E.coli, C-terminal 6xHis-tagged, 62.8kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Tyrosine-protein kinase Srms (Srms)

Recombinant Mouse Tyrosine-protein kinase Srms (Srms) — Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Purity >90%.

SKU: BCRECP-004482 Categories: , ,
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Product Specifications

Product SkuBCRECP-004482
Product DescriptionRecombinant Mouse Tyrosine-protein kinase Srms (Srms) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-496aa. [Accession | Q62270].
Uniprot No.Q62270
Gene NamesSrms
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-496aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight62.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent.

Biological Context

Subcellular Location: Cytoplasm
Tissue Specificity: Higher expression in liver, lung, thymus and skin than in brain, kidney, heart and spleen. In skin, highly expressed in keratinocytes. Abundant in lung, liver, spleen, kidney and testis and is also detected in the cerebrum

Product Specifications

Recombinant Mouse Tyrosine-protein kinase Srms (Srms) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-496aa, with C-terminal 6xHis-tagged tag, molecular weight 62.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent. Phosphorylates OTUB1, promoting deubiquitination of RPTOR

Subcellular Location

Cytoplasm

Tissue Specificity

Higher expression in liver, lung, thymus and skin than in brain, kidney, heart and spleen (PubMed:9226137). In skin, highly expressed in keratinocytes (PubMed:9226137). Abundant in lung, liver, spleen, kidney and testis and is also detected in the cerebrum (PubMed:7935409)

Subunit

Interacts (via the SH2 and SH3 domains) with DOK1. Interacts with KHDRBS1/SAM68 and VIM

Gene: Srms  |  Organism: Mus musculus  |  Synonyms: PTK70

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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