Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial, Gorilla gorilla gorilla (Western lowland gorilla), E.coli, C-terminal 6xHis-tagged, 15.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial — G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Purity >85%.

SKU: BCRECP-003019 Category:
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Product Specifications

Product SkuBCRECP-003019
Product DescriptionRecombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 290-359aa. [Accession | Q76MS7].
Uniprot No.Q76MS7
Gene NamesHRH2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region290-359aa
SpeciesGorilla gorilla gorilla (Western lowland gorilla)
Tag InfoC-terminal 6xHis-tagged
Molecular weight15.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels. This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial is a recombinant protein from Gorilla gorilla gorilla (Western lowland gorilla), expressed in E.coli, covering amino acids 290-359aa, with C-terminal 6xHis-tagged tag, molecular weight 15.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels (By similarity). This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology. Also expressed in other tissues, including the heart and central nervous system, where it may contribute to cardiac stimulation and modulate neurotransmitter release (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

Interacts with GNAS

Gene: HRH2  |  Organism: Gorilla gorilla gorilla  |  Synonyms: Gastric receptor I

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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