Recombinant Human IL23 23-328aa (IL12B) / 20-189aa (IL23A) Protein, Baculovirus-Insect Cells, N-6His, 34.6kDa (IL12B) & 19.5kDa (IL23A) (306aa & 176aa), purity >90% as determined by SDS-PAGE.

Recombinant Human IL23 23-328aa (IL12B) / 20-189aa (IL23A) Protein

Recombinant Human IL23 23-328aa (IL12B) / 20-189aa (IL23A) Protein — Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. Purity >90%.

SKU: BCRETP-000020 Category:
Online Inquiry →

Product Specifications

Product SkuBCRETP-000020
Product DescriptionRecombinant Human IL23 23-328aa (IL12B) / 20-189aa (IL23A) Protein is expressed from Baculovirus-Insect Cells with His tag at the N-Terminus. It contains 23-328aa/20-189aa. [Accession | P29460；Q9NPF7].
Uniprot No.P29460；Q9NPF7
SynonymsInterleukin-12 subunit beta / Interleukin-23 subunit alpha, CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2/ IL-23, IL-23A, IL23P19, P19, SGRF
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemBaculovirus-Insect Cells
Expression Region23-328aa/20-189aa
Tag InfoN-6His
Molecular weight34.6kDa (IL12B) & 19.5kDa (IL23A) (306aa & 176aa)
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.

Product Specifications

Recombinant Human IL23 23-328aa (IL12B) / 20-189aa (IL23A) Protein is a recombinant protein, expressed in Baculovirus-Insect Cells, covering amino acids 23-328aa/20-189aa, with N-6His tag, molecular weight 34.6kDa (IL12B) & 19.5kDa (IL23A) (306aa & 176aa), purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis

Gene: IL12B  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top