Recombinant Human Low-density lipoprotein receptor (LDLR), partial, Homo sapiens (Human), Mammalian cell, Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially., 89.2 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Low-density lipoprotein receptor (LDLR), partial

Recombinant Human Low-density lipoprotein receptor (LDLR), partial — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000110 Category:
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Product SKUBCACP-000110
Product DescriptionRecombinant Human Low-density lipoprotein receptor (LDLR) protein is expressed from Mammalian cell with Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.. It contains 22-788aa. [Accession | P01130].
Uniprot No.P01130
Gene NamesLDLR
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-788aa
SpeciesHomo sapiens (Human)
Tag InfoTag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Molecular weight89.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized CD30 at 5 μg/ml can bind human CD30L, the EC50 is 4.169-6.360 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesLDL receptor

Function

(Microbial infection) Acts as a receptor for many Alphavirus, including Getah virus (GETV), Ross river virus (RRV) and Semliki Forest virus.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Membrane, clathrin-coated pit; Golgi apparatus; Early endosome; Late endosome; Lysosome
Disease Association: Hypercholesterolemia, familial, 1 (FHCL1) : A form of hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum low-density lipoprotein (LDL) cholesterol levels, which result in excess deposition of cholesterol in tissues and leads to xanthelasma, xanthomas, accelerated atherosclerosis and increased risk of premature coronary heart disease. FHCL1 inheritance is autosomal dominant. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Low-density lipoprotein receptor (LDLR), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 22-788aa, with Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. tag, molecular weight 89.2 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Acts as a receptor for many Alphavirus, including Getah virus (GETV), Ross river virus (RRV) and Semliki Forest virus

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Membrane, clathrin-coated pit; Golgi apparatus; Early endosome; Late endosome; Lysosome

Disease Association

Hypercholesterolemia, familial, 1 (FHCL1) : A form of hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum low-density lipoprotein (LDL) cholesterol levels, which result in excess deposition of cholesterol in tissues and leads to xanthelasma, xanthomas, accelerated atherosclerosis and increased risk of premature coronary heart disease. FHCL1 inheritance is autosomal dominant. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

(Microbial infection) May interact with HIV-1 Tat

Gene: LDLR  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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