Recombinant Human Persephin protein (PSPN), partial (Active), Homo sapiens (Human), E.Coli, Tag-Free, 10.3 kDa, purity >>97% as determined by SDS-PAGE.

Recombinant Human Persephin protein (PSPN), partial (Active)

Recombinant Human Persephin protein (PSPN), partial (Active) — Growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Purity >97%.

SKU: BCACP-000856 Category:
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Product SKUBCACP-000856
Product DescriptionRecombinant Human Persephin protein (PSPN) protein is expressed from E.Coli with Tag-Free. It contains 61-156aa. [Accession | O60542].
Uniprot No.O60542
Gene NamesPSPN
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region61-156aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight10.3 kDa
ActivityThe biological activity is determined by chromogenic assay, 1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin. The specific activity is no less than 14,000 ATU/mg protein.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesPSPN; Persephin; PSP

Function

Growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Persephin protein (PSPN), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 61-156aa, with Tag-Free tag, molecular weight 10.3 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (PubMed:11116144, PubMed:9491986). Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor (PubMed:11116144)

Subcellular Location

Secreted

Subunit

Homodimer; disulfide-linked (By similarity). Interacts with GFRA4 coreceptor and RET: forms a 2:2:2 ternary complex composed of PSPN ligand, GFRA4 and RET receptor (Probable)

Gene: PSPN  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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