Recombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4), partial (Active), Mus musculus (Mouse), Mammalian cell, C-terminal 6xHis-tagged, 14.6 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4), partial (Active)

Recombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4), partial (Active) — Inhibitory receptor acting as a major negative regulator of T-cell responses. Purity >95%.

SKU: BCACP-001285 Categories: ,
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Product SKUBCACP-001285
Product DescriptionRecombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4) protein is expressed from Mammalian cell with C-terminal 6xHis-tagged. It contains 37-161aa. [Accession | P09793].
Uniprot No.P09793
Gene NamesCtla4
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region37-161aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight14.6 kDa
ActivityThe ED50 as determined by its ability to bind Mouse SIRPA in functional ELISA is less than 20 ug/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCtla4; Cd152; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152

Function

Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Product Specifications

Recombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 37-161aa, with C-terminal 6xHis-tagged tag, molecular weight 14.6 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28

Gene: Ctla4  |  Organism: Mus musculus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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