Recombinant Human Mesothelin (MSLN), partial (Active), Homo sapiens (Human), Mammalian cell, N-terminal hFc-tagged, 59.6 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Mesothelin (MSLN), partial (Active)

Recombinant Human Mesothelin (MSLN), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000006 Category:
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Product SKUBCACP-000006
Product DescriptionRecombinant Human Mesothelin (MSLN) protein is expressed from Mammalian cell with N-terminal hFc-tagged. It contains 296-580aa. [Accession | Q13421].
Uniprot No.Q13421
Gene NamesMSLN
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region296-580aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal hFc-tagged
Molecular weight59.6 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized MSLN at 2 μg/ml can bind Anti-MSLN rabbit monoclonal antibody, the EC50 of the MSLN protein is 2.657-3.177 ng/ml.;Measured by its binding ability in a functional ELISA. Immobilized MUC16 at 10 μg/ml can bind MSLN, the EC50 is 460.7-662.2 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCAK 1; CAK1; CAK1 antigen; cleaved form; Megakaryocyte potentiating factor ; Mesothelin; Mesothelin isoform 1 precursor ; MPF; Msln; MSLN_HUMAN; Pre pro megakaryocyte potentiating factor; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; Soluble MPF mesothelin related protein

Function

Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level)
Disease Association: [Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer]

Product Specifications

Recombinant Human Mesothelin (MSLN), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 296-580aa, with N-terminal hFc-tagged tag, molecular weight 59.6 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized MSLN at 2 μg/ml can bind Anti-MSLN rabbit monoclonal antibody, the EC50 of the MSLN protein is 2.657-3.177 ng/ml.;Measured by its binding ability in a functional ELISA. Immobilized MUC16 at 10 μg/ml can bind MSLN, the EC50 is 460.7-662.2 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro

Subcellular Location

Secreted

Disease Association

[Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer]

Tissue Specificity

Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level)

Subunit

Interacts with MUC16

Gene: MSLN  |  Organism: Homo sapiens  |  Synonyms: CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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