Recombinant Mouse Short transient receptor potential channel 1 (Trpc1) Protein, Mus musculus (Mouse), in vitro E.coli expression system, N-terminal 10xHis-tagged, 94.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Short transient receptor potential channel 1 (Trpc1) Protein

Recombinant Mouse Short transient receptor potential channel 1 (Trpc1) Protein — Forms a receptor-activated non-selective calcium permeant cation channel. Purity >85%.

SKU: BCRECP-00182TM Category:
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Product Specifications

Uniprot No.Q61056
Gene NamesTrpc1
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-793aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged
Molecular weight94.0kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Mouse Short transient receptor potential channel 1 (Trpc1) Protein is a recombinant protein from Mus musculus (Mouse), expressed in in vitro E.coli expression system, covering amino acids 1-793aa, with N-terminal 10xHis-tagged tag, molecular weight 94.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel (By similarity). Also permeable to monovalent ions including sodium, lithium and cesium ions (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

Heterotetramer with TRPC4 and/or TRPC5 (By similarity). Forms a heteromeric ion channel with TRPC4, with a 1:3 TRPC1:TRPC4 stoichiometry (By similarity). Unlike other TRP channel proteins, does not form a homomeric channel (By similarity). Interacts with TRPC4AP (PubMed:20458742). Interacts with ITPR3 (By similarity). Interacts with MX1 and RNF24 (By similarity). Interacts with FKBP4 (By similarity). Interacts with PLSCR1 (PubMed:32110987). Interacts with PKD2L2 (By similarity). Forms a heterotetramer with PKD2 with a 2:2 stoichiometry; has distinct channel properties separate from PKD2 or TRPC1 homomers alone (By similarity)

Gene: Trpc1  |  Organism: Mus musculus  |  Synonyms: Transient receptor protein 1; Trp-related protein 1

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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