Transmembrane Proteins for Research

BioCrestSci supplies transmembrane proteins for research across antibody discovery, ligand–receptor studies, drug screening and structural biology. Membrane proteins are challenging targets because their conformation and activity can depend on the surrounding lipid or detergent environment. Our catalog brings together multiple presentation formats and expression strategies so researchers can choose a reagent suited to the target and experimental workflow.

Explore receptors, channels, transporters and other single-pass or multi-pass membrane targets from multiple species. Available formats include VLP-displayed proteins, nanodisc proteins and product-specific soluble or detergent-compatible preparations. Each product page provides the relevant construct, expression system, tag, formulation and available quality information to support comparison before ordering.

For antibody campaigns, consider whether native-like membrane presentation and extracellular epitope accessibility are priorities. For binding or structural studies, evaluate solubility, lipid composition, orientation and assay compatibility. When the required target, construct or format is not listed, BioCrestSci can support custom membrane protein expression and production.

Multiple FormatsVLP, nanodisc and product-specific preparations
Diverse TargetsReceptors, channels, transporters and more
Research UsesAntibody discovery, binding, screening and structure
Custom SupportConstruct design, expression and production options

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Choose a Transmembrane Protein Format for Your Workflow

Membrane proteins depend on their surrounding lipid or detergent environment, so the best reagent format depends on the target and experiment. Review each product page for construct boundaries, expression system, tag, formulation and available characterization data before ordering.

VLP-Displayed Proteins

VLP presentation supports antibody discovery and immunization workflows that benefit from membrane-embedded targets and accessible extracellular epitopes. Explore the VLP transmembrane protein collection.

Research Applications

Antibody Discovery

Select targets and formats for immunization, hybridoma or display-library screening, epitope recognition and binder characterization.

Binding, Screening and Structure

Membrane protein reagents can support SPR/BLI, ligand-binding studies, target validation, drug screening and structural biology when the chosen format is compatible with the assay.

Catalog Products and Custom Production

For targets not available in the catalog—or when a specific construct, orientation or membrane format is required—review BioCrestSci's transmembrane protein expression service, membrane protein production service and full-length multi-pass expression platform.

Transmembrane Protein FAQ

Which membrane protein format should I choose?

Choose according to the target and assay. VLP formats are often suited to immunization and antibody screening, while nanodiscs can support detergent-free binding and structural studies. Check product-specific specifications.

Can I request a transmembrane protein that is not listed?

Yes. Custom expression and production services are available for targets requiring a different construct, expression strategy or membrane presentation format.

What information should I review before ordering?

Review the sequence region, expression system, tag, formulation, membrane format and available QC or functional information on the individual product page.

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