Recombinant Human Filamin A-interacting protein 1-like (FILIP1L), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-GST-tagged, 55.1kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Filamin A-interacting protein 1-like (FILIP1L), partial

Recombinant Human Filamin A-interacting protein 1-like (FILIP1L), partial — Acts as a regulator of the antiangiogenic activity on endothelial cells. Purity >85%.

SKU: BCRECP-000677 Category:
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Product Specifications

Product SkuBCRECP-000677
Product DescriptionRecombinant Human Filamin A-interacting protein 1-like (FILIP1L) Protein is expressed from E.coli with N-terminal 6xHis-GST-tagged. It contains 1-200aa. [Accession | Q4L180].
Uniprot No.Q4L180
Gene NamesFILIP1L
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-200aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-GST-tagged
Molecular weight55.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.

Biological Context

Subcellular Location: Cytoplasm; Membrane; Nucleus
Tissue Specificity: Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer

Product Specifications

Recombinant Human Filamin A-interacting protein 1-like (FILIP1L), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-200aa, with N-terminal 6xHis-GST-tagged tag, molecular weight 55.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature

Subcellular Location

Cytoplasm; Membrane; Nucleus

Tissue Specificity

Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer

Gene: FILIP1L  |  Organism: Homo sapiens  |  Synonyms: 130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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