Recombinant Human Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1), partial, Homo sapiens (Human), Yeast, N-terminal 6xHis-tagged, 26.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1), partial

Recombinant Human Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1), partial — Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Purity >90%.

SKU: BCRECP-001010 Category:
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Product Specifications

Product SkuBCRECP-001010
Product DescriptionRecombinant Human Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 22-245aa. [Accession | Q14954].
Uniprot No.Q14954
Gene NamesKIR2DS1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region22-245aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight26.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed by NK cells

Product Specifications

Recombinant Human Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1), partial is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 22-245aa, with N-terminal 6xHis-tagged tag, molecular weight 26.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed by NK cells

Subunit

Interacts with the adapter protein TYROBP/DAP12; the interaction enhances KIR2DS1 stability at the cell surface

Gene: KIR2DS1  |  Organism: Homo sapiens  |  Synonyms: CD158 antigen-like family member H; MHC class I NK cell receptor Eb6 ActI
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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