Recombinant Human TNFRSF1A Protein, HEK293 Cells, C-His, 22.7 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human TNFRSF1A Protein

Recombinant Human TNFRSF1A Protein — Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. Purity >95%.

SKU: BCRETP-000007 Categories: ,
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Product Specifications

Product SkuBCRETP-000007
Product DescriptionRecombinant Human TNFRSF1A Protein is expressed from HEK293 with His tag at the C-Terminus. It contains 1-211aa. [Accession | P19438].
Uniprot No.P19438
SynonymsCD120a;FPF;MS5;p55;p55-R;p60;TBP1;TNF-R;TNF-R-I;TNF-R55;TNFAR;TNFR1;TNFR1-d2;TNFR55;TNFR60
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemHEK293 Cells
Expression Region1-211aa
Tag InfoC-His
Molecular weight22.7 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Product Specifications

Recombinant Human TNFRSF1A Protein is a recombinant protein, expressed in HEK293 Cells, covering amino acids 1-211aa, with C-His tag, molecular weight 22.7 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase

Gene: TNFRSF1A  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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