Recombinant Human TNFRSF1A Protein, HEK293 Cells, C-His, 22.7 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human TNFRSF1A Protein

Recombinant Human TNFRSF1A Protein — Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. Purity >95%.

SKU: BCRETP-000007 Categories: ,
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Product Specifications

Product SkuBCRETP-000007
Product DescriptionRecombinant Human TNFRSF1A Protein is expressed from HEK293 with His tag at the C-Terminus. It contains 1-211aa. [Accession | P19438].
Uniprot No.P19438
SynonymsCD120a;FPF;MS5;p55;p55-R;p60;TBP1;TNF-R;TNF-R-I;TNF-R55;TNFAR;TNFR1;TNFR1-d2;TNFR55;TNFR60
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemHEK293 Cells
Expression Region1-211aa
Tag InfoC-His
Molecular weight22.7 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Product Specifications

Recombinant Human TNFRSF1A Protein is a recombinant protein, expressed in HEK293 Cells, covering amino acids 1-211aa, with C-His tag, molecular weight 22.7 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase

Gene: TNFRSF1A  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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