Function
Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
Biological Context
Subcellular Location: Nucleus
Tissue Specificity: Expressed at low levels in normal tissues, with highest expression levels in placenta and testis. Expression is significantly increased in subset of diffuse large B-cell lymphomas
Product Specifications
Recombinant Human MORC family CW-type zinc finger protein 4 (MORC4), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 29-486aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 57.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
