Recombinant Human Parathyroid hormone-related protein (PTHLH), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 19.7kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Parathyroid hormone-related protein (PTHLH), partial

Recombinant Human Parathyroid hormone-related protein (PTHLH), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-001471 Category:
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Product Specifications

Product SkuBCRECP-001471
Product DescriptionRecombinant Human Parathyroid hormone-related protein (PTHLH) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 37-175aa. [Accession | P12272].
Uniprot No.P12272
Gene NamesPTHLH
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region37-175aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight19.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Potent inhibitor of osteoclastic bone resorption.

Biological Context

Subcellular Location: Secreted; Cytoplasm; Nucleus
Tissue Specificity: Ubiquitous. Also expressed in the mammary gland
Disease Association: Brachydactyly E2 (BDE2) : A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. Brachydactyly type E is characterized by shortening of the fingers mainly in the metacarpals and metatarsals. Wide variability in the number of digits affected occurs from person to person, even in the same family. Some individuals are moderately short of stature. In brachydactyly type E2 variable combinations of metacarpals are involved, with shortening also of the first and third distal and the second and fifth middle phalanges. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Parathyroid hormone-related protein (PTHLH), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 37-175aa, with N-terminal 6xHis-tagged tag, molecular weight 19.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Potent inhibitor of osteoclastic bone resorption

Subcellular Location

Secreted; Cytoplasm; Nucleus

Disease Association

Brachydactyly E2 (BDE2) : A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. Brachydactyly type E is characterized by shortening of the fingers mainly in the metacarpals and metatarsals. Wide variability in the number of digits affected occurs from person to person, even in the same family. Some individuals are moderately short of stature. In brachydactyly type E2 variable combinations of metacarpals are involved, with shortening also of the first and third distal and the second and fifth middle phalanges. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Ubiquitous. Also expressed in the mammary gland

Subunit

Interacts with PTH1R (via N-terminal extracellular domain)

Gene: PTHLH  |  Organism: Homo sapiens  |  Synonyms: Parathyroid hormone-like protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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