Function
May play a role in vesicle trafficking. Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes.
Biological Context
Subcellular Location: Cell membrane (Peripheral membrane protein)
Tissue Specificity: Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL)
Product Specifications
Recombinant Human Synaptotagmin-like protein 1 (SYTL1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-562aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 66.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
