Recombinant Interleukin 18 Receptor 1 (IL18R1), 293F cell, Fc, 6×His tag at the C-terminus, 80 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Interleukin 18 Receptor 1 (IL18R1)

Recombinant Interleukin 18 Receptor 1 (IL18R1) — Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Purity >90%.

SKU: BCRETP-000005 Categories: ,
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Product Specifications

Product SkuBCRETP-000005
Product DescriptionRecombinant Interleukin 18 Receptor 1 (IL18R1) is expressed from HEK293F with Fc tag at the C-Terminus. It contains 20-329aa. [Accession | Q13478].
Uniprot No.Q13478
SynonymsCDw218a; CD218a; IL18-R1; IL-1Rrp; IL1RRP; CD218 antigen-like family member A; IL1 receptor-related protein
PurityGreater than 90% as determined by SDS-PAGE.
Expression System293F cell
Expression Region20-329aa
Tag InfoFc, 6×His tag at the C-terminus
Molecular weight80 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.

Product Specifications

Recombinant Interleukin 18 Receptor 1 (IL18R1) is a recombinant protein, expressed in 293F cell, covering amino acids 20-329aa, with Fc, 6×His tag at the C-terminus tag, molecular weight 80 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:14528293, PubMed:25261253, PubMed:25500532, PubMed:37993714, PubMed:8626725). Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity)

Gene: IL18R1  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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