Recombinant Human Tropomodulin-1 (TMOD1), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 67.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Tropomodulin-1 (TMOD1)

Recombinant Human Tropomodulin-1 (TMOD1) — Blocks the elongation and depolymerization of the actin filaments at the pointed end. Purity >90%.

SKU: BCRECP-001785 Category:
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Product Specifications

Product SkuBCRECP-001785
Product DescriptionRecombinant Human Tropomodulin-1 (TMOD1) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-359aa. [Accession | P28289].
Uniprot No.P28289
Gene NamesTMOD1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-359aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight67.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

Biological Context

Subcellular Location: Cytoplasm, cytoskeleton
Tissue Specificity: Highly expressed in the erythrocyte, heart and skeletal muscle

Product Specifications

Recombinant Human Tropomodulin-1 (TMOD1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-359aa, with N-terminal GST-tagged tag, molecular weight 67.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Blocks the elongation and depolymerization of the actin filaments at the pointed end (PubMed:38168645). The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus

Subcellular Location

Cytoplasm, cytoskeleton

Tissue Specificity

Highly expressed in the erythrocyte, heart and skeletal muscle

Subunit

Binds to the N-terminus of tropomyosin and to actin. Interacts with FLII

Gene: TMOD1  |  Organism: Homo sapiens  |  Synonyms: Erythrocyte tropomodulin
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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