Recombinant Human Tumor necrosis factor receptor superfamily member 1B Protein, Insect cell, N-6His, 25.9kDa (241aa) 28-40KDa (SDS-PAGE under reducing conditions.), purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 1B Protein

Recombinant Human Tumor necrosis factor receptor superfamily member 1B Protein — Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. Purity >95%.

SKU: BCRETP-000018 Categories: ,
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Product Specifications

Product SkuBCRETP-000018
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 1B Protein is expressed from Insect Cells with His tag at the N-Terminus. It contains 23-257aa. [Accession | P20333].
Uniprot No.P20333
SynonymsTNFRSF1B, CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemInsect cell
Expression Region23-257aa
Tag InfoN-6His
Molecular weight25.9kDa (241aa) 28-40KDa (SDS-PAGE under reducing conditions.)
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF.

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 1B Protein is a recombinant protein, expressed in Insect cell, covering amino acids 23-257aa, with N-6His tag, molecular weight 25.9kDa (241aa) 28-40KDa (SDS-PAGE under reducing conditions.), purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity

Gene: TNFRSF1B  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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