Recombinant Human Thyrotropin subunit beta (TSHB), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 28.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Thyrotropin subunit beta (TSHB)

Recombinant Human Thyrotropin subunit beta (TSHB) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-001862 Category:
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Product Specifications

Product SkuBCRECP-001862
Product DescriptionRecombinant Human Thyrotropin subunit beta (TSHB) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 21-132aa. [Accession | P01222].
Uniprot No.P01222
Gene NamesTSHB
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region21-132aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight28.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Indispensable for the control of thyroid structure and metabolism.

Biological Context

Subcellular Location: Secreted
Disease Association: Hypothyroidism, congenital, non-goitrous, 4 (CHNG4) : A form of central hypothyroidism, a disorder characterized by insufficient stimulation by thyroid stimulating hormone of an otherwise normal thyroid gland. CHNG4 is an autosomal recessive form characterized by isolated thyrotropin deficiency that, if untreated, results in severe growth retardation and intellectual disability. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Thyrotropin subunit beta (TSHB) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 21-132aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 28.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Indispensable for the control of thyroid structure and metabolism

Subcellular Location

Secreted

Disease Association

Hypothyroidism, congenital, non-goitrous, 4 (CHNG4) : A form of central hypothyroidism, a disorder characterized by insufficient stimulation by thyroid stimulating hormone of an otherwise normal thyroid gland. CHNG4 is an autosomal recessive form characterized by isolated thyrotropin deficiency that, if untreated, results in severe growth retardation and intellectual disability. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin

Gene: TSHB  |  Organism: Homo sapiens  |  Synonyms: Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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