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Recombinant African swine fever virus CD2 homolog, partial

Recombinant African swine fever virus CD2 homolog, partial — May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection. Purity >95%.

SKU: BCRECP-003781 Categories: , ,

Product Specifications

Product SkuBCRECP-003781
Product DescriptionRecombinant African swine fever virus CD2 homolog, partial Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 17-204aa. [Accession | Q89501].
Uniprot No.Q89501
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region17-204aa
SpeciesAfrican swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Tag InfoC-terminal hFc1-tagged
Molecular weight50.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection. Responsible for viral hemadsorption, which may help viral spread. Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut.

Biological Context

Subcellular Location: Host cell membrane (Single-pass type I membrane protein); Virion membrane; Host Golgi apparatus

Product Specifications

Recombinant African swine fever virus CD2 homolog, partial is a recombinant protein from African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV), expressed in Mammalian cell, covering amino acids 17-204aa, with C-terminal hFc1-tagged tag, molecular weight 50.4kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection (By similarity). Responsible for viral hemadsorption, which may help viral spread (PubMed:8102411, PubMed:8615037). Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut (PubMed:19729182). May play a role in the host Golgi reorganization to yield viral factories (PubMed:25915900). May play a role in host cell penetration (PubMed:34006158)

Subcellular Location

Host cell membrane (Single-pass type I membrane protein); Virion membrane; Host Golgi apparatus

Subunit

Both glycosylated and nonglycosylated forms interact (via C-terminus) with the host AP-1 complex

Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted)  |  Synonyms: 5HL; CD2v; T-lymphocyte CD2 receptor-like protein; pEP402R
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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