Recombinant Mouse Somatostatin (Sst), partial, Mus musculus (Mouse), E.coli, N-terminal 6xHis-KSI-tagged, 18.5kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Somatostatin (Sst), partial

Recombinant Mouse Somatostatin (Sst), partial — May enhance low-glucose-induced glucagon release by pancreatic alpha cells. Purity >85%.

SKU: BCRECP-004490 Category:
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Product Specifications

Product SkuBCRECP-004490
Product DescriptionRecombinant Mouse Somatostatin (Sst) Protein is expressed from E.coli with N-terminal 6xHis-KSI-tagged. It contains 89-116aa. [Accession | P60041].
Uniprot No.P60041
Gene NamesSst
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region89-116aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-KSI-tagged
Molecular weight18.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

May enhance low-glucose-induced glucagon release by pancreatic alpha cells. This effect may be mediated by binding to GPR107 and PKA activation. May regulate cardiac contractile function.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: In the pancreas, somatostatin is expressed in delta cells of the islets of Langerhans. In the stomach, it is expressed in parietal cells of oxyntic mucosa and in the small intestine, it is found in the villus (at protein level). Neuronostatin is expressed in the pancreas in delta cells of the islets of Langerhans, as well as in the stomach, in parietal cells of oxyntic mucosa and in the small intestine, in the villus (at protein level)

Product Specifications

Recombinant Mouse Somatostatin (Sst), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 89-116aa, with N-terminal 6xHis-KSI-tagged tag, molecular weight 18.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

May enhance low-glucose-induced glucagon release by pancreatic alpha cells (PubMed:24735892). This effect may be mediated by binding to GPR107 and PKA activation (PubMed:26561648). May regulate cardiac contractile function (PubMed:25012062). May compromise cardiomyocyte viability (By similarity). In the central nervous system, may impair memory retention and may affect hippocampal excitability (By similarity). May also have anxiolytic and anorexigenic effects (By similarity). May play a role in arterial pressure regulation (By similarity). May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH (By similarity). Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity)

Subcellular Location

Secreted

Tissue Specificity

In the pancreas, somatostatin is expressed in delta cells of the islets of Langerhans. In the stomach, it is expressed in parietal cells of oxyntic mucosa and in the small intestine, it is found in the villus (at protein level) (PubMed:18753129). Neuronostatin is expressed in the pancreas in delta cells of the islets of Langerhans, as well as in the stomach, in parietal cells of oxyntic mucosa and in the small intestine, in the villus (at protein level) (PubMed:18753129)

Gene: Sst  |  Organism: Mus musculus
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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