Function
Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Binds high molecular weight sulfated glycosaminoglycans.
Biological Context
Subcellular Location: Cell membrane (Single-pass type II membrane protein)
Tissue Specificity: Detected in fetal heart, brain, lung, chondrocytes, perichondrium and osteoblasts, and in adult splenocytes, thymocytes, lymph-node cells, osteoblasts, growth plate chondrocytes and skeletal muscle overlying the bone (at protein level). Ubiquitous. Detected in thymus, bone marrow, lung, gut, heart, skeletal muscle, ovary, spleen, ileum, liver and kidney
Product Specifications
Recombinant Mouse C-type lectin domain family 2 member D (Clec2d), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 63-207aa, with N-terminal 6xHis-tagged tag, molecular weight 21.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
