Function
Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The CIV complex is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Acts as an assembly factor that specifically drives the homodimerization of CIV complexes, mediating the formation of mitochondrial respiratory supercomplexes (respirasomes) containing two CIV: supercomplxes with two molecules of CIV show improved activity.
Biological Context
Subcellular Location: Mitochondrion inner membrane (Single-pass membrane protein)
Pathway: Energy metabolism; oxidative phosphorylation
Product Specifications
Recombinant Trachypithecus cristatus Cytochrome c oxidase subunit 7A1, mitochondrial (COX7A1), partial is a recombinant protein from Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata), expressed in E.coli, covering amino acids 22-46aa, with N-terminal 6xHis-KSI-tagged tag, molecular weight 18.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Enzyme proteins →
