Compare BioCrest Sci IL-6 recombinant proteins by species, expression system, tag, activity, endotoxin specification and format. This product family includes human, mouse, bovine, cynomolgus monkey, sheep and other species, with active, tag-free, biotinylated, GMP and ultra-low endotoxin options for research use.
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Find the Right IL-6 Recombinant Protein
Interleukin-6 (IL-6; gene symbol IL6) products can differ in species, sequence region, expression system, purification tag, purity, endotoxin level and biological activity. Select the product that matches the intended assay rather than treating all IL-6 preparations as interchangeable.
- Functional and cell-based studies: prioritize products with product-specific biological activity data.
- Endotoxin-sensitive workflows: compare the stated endotoxin specification on the individual product page or lot documentation.
- Binding and detection: consider biotinylated, Avi-tagged, Fc-tagged or His-tagged formats according to the assay design.
- Process-oriented research: review the GMP-designated option and confirm current documentation before ordering.
IL-6 Recombinant Protein Comparison
The table below highlights representative catalog options with clearly available product information. Specifications are product-specific; open the product page to review sequence, formulation, storage, current pack sizes and supporting documentation.
| Species | Format | Expression system | Tag | Purity / endotoxin | Activity | SKU | Product |
|---|---|---|---|---|---|---|---|
| Human | Standard | Mammalian cell | C-terminal 10×His | See product page | Not stated | BCACP-990234 | View product |
| Human | Tag-free | E. coli | Tag-free | See product page | Not stated | BCACP-830453 | View product |
| Human | Biotinylated | Mammalian cell | N-terminal human Fc; C-terminal Avi | See product page | Not stated | BCACP-980244 | View product |
| Human | Active | E. coli | Tag-free | >95% by SDS-PAGE | Product designated Active | BCACP-001004 | View product |
| Human | Active, GMP | E. coli | Tag-free | >98% by SDS-PAGE and HPLC | Product designated Active | BCACP-001059 | View product |
| Human | Active, ultra-low endotoxin | CHO | Not specified | ≥95%; ≤10 EU/mg | M-NFS-60 proliferation assay; ED50 0.2–1 ng/mL | BIC-5389E | View product |
| Mouse | Standard | Yeast | C-terminal 10×His | See product page | Not stated | BCACP-755065 | View product |
| Mouse | Standard | Mammalian cell | N-terminal 10×His | See product page | Not stated | BCACP-817007 | View product |
| Mouse | Active, ultra-low endotoxin | HEK293 | See product page | ≥95%; ≤10 EU/mg | M-NFS-60 proliferation assay; reported ED50 <0.5 ng/mL | BIC-7458E | View product |
| Bovine | Active, ultra-low endotoxin | E. coli | Not specified | ≥95%; ≤10 EU/mg | M-NFS-60 proliferation assay; ED50 ≤0.1 ng/mL | BIC-2712E | View product |
| Cynomolgus monkey | Fc-tagged | Mammalian cell | C-terminal human Fc | See product page | Not stated | BCACP-713223 | View product |
| Cynomolgus monkey | His-tagged | Mammalian cell | N-terminal 10×His | See product page | Not stated | BCACP-786974 | View product |
| Sheep | His-tagged | Yeast | N-terminal 6×His | See product page | Not stated | BCACP-616686 | View product |
Need a different species or construct? Browse the complete Interleukins catalog or send the target species, application and required format.
IL-6 Formats Available from BioCrest Sci
Active IL-6 Proteins
For cell-based and functional experiments, choose a product whose page reports an appropriate activity method and potency result. The activity designation alone should not replace review of the actual assay and lot documentation.
Ultra-Low Endotoxin IL-6 Proteins
Human, mouse and bovine active IL-6 options are available with product-specific endotoxin specifications. Compare the stated limit and confirm lot-specific requirements for sensitive cell-based workflows. Browse ultra-low endotoxin proteins.
Biotinylated IL-6 Proteins
Biotinylated and Avi-tagged formats can support immobilization, detection and binding workflows. Confirm the tag arrangement and assay compatibility on the selected product page. Browse biotinylated proteins.
Tag-Free, His-Tagged and Fc-Tagged IL-6
Tag-free formats may be preferred when a fusion tag could interfere with downstream use. His-tagged products can simplify capture or detection, while Fc-tagged formats may be useful in selected binding workflows. The optimal format depends on the experiment.
How to Select an IL-6 Protein
- Match the species. Start with the species required by the biological system or assay.
- Confirm the construct. Review accession, sequence region and molecular weight on the product page.
- Choose the expression system. Compare bacterial, yeast, mammalian and CHO-derived options according to folding, modifications and downstream requirements.
- Review the tag. Select tag-free, His, Fc or Avi/biotinylated formats based on immobilization, detection and functional needs.
- Check product-specific QC. Verify purity, endotoxin, activity, formulation and storage; do not assume specifications across SKUs.
- Confirm price and availability. Submit the SKU, required quantity, destination and application for a current quotation.
Frequently Asked Questions
Which IL-6 recombinant protein should I use for a cell-based assay?
Use an active IL-6 product with a product-specific biological activity assay relevant to the planned workflow. Also check species compatibility, endotoxin specification, formulation and carrier status.
Are human and mouse IL-6 interchangeable?
No. Species sequence and receptor compatibility can affect experimental performance. Select the species supported by the assay and review the individual product data.
When should I choose biotinylated IL-6?
Biotinylated IL-6 can be useful for capture, detection, immobilization and selected binding assays. Confirm the biotinylation or Avi-tag configuration and make sure it fits the assay design.
Does every IL-6 product have the same endotoxin level or biological activity?
No. Purity, endotoxin and biological activity are SKU-specific. Only rely on values stated on the individual product page, datasheet or Certificate of Analysis.
Can BioCrest Sci provide an alternative IL-6 construct?
If a catalog format does not match the required species, sequence, expression system, tag or scale, submit the project requirements through the custom protein expression service.
Request IL-6 Price and Availability
Include the product SKU, quantity, delivery country, intended application and any purity, endotoxin, activity or documentation requirements. BioCrest Sci will confirm current availability, pack sizes, pricing and estimated dispatch timing.
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For research use only. Product specifications and availability are subject to confirmation on the individual product page and current quotation.