Mouse anti-Human/Mouse/Rat CCNB1 Monoclonal Antibody — Essential for the control of the cell cycle at the G2/M (mitosis) transition.
| Uniprot No. | P14635 |
| Target Names | CCNB1 |
| Species Reactivity | Mouse |
| Immunogen | Synthetic Peptide of Cyclin B1 at AA range of 60-140 |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | Non-conjugated |
| Clonality | Monoclonal |
| Applications | ELISA,IHC |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Essential for the control of the cell cycle at the G2/M (mitosis) transition. Binds and activates cyclin-dependent protein kinase CDK1/CDC2.
Subcellular Location: Cytoplasm; Nucleus; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Mouse anti-Human/Mouse/Rat CCNB1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications. Explore more Antibody products →
Applications: ELISA,IHC
Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
Essential for the control of the cell cycle at the G2/M (mitosis) transition (PubMed:27030811, PubMed:17495531, PubMed:17495533). Binds and activates cyclin-dependent protein kinase CDK1/CDC2 (PubMed:41100585)
Cytoplasm; Nucleus; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Interacts with the CDK1/CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex known as maturation promoting factor (MPF) (PubMed:41100585). The cyclin subunit imparts substrate specificity to the complex. Binds HEI10. Interacts with catalytically active RALBP1 and CDK1/CDC2 during mitosis to form an endocytotic complex during interphase. Interacts with CCNF; interaction is required for nuclear localization. Interacts with CDK5RAP3 (PubMed:15790566). Interacts with RFPL4A and UBE2A (By similarity). Interacts with INCA1 (PubMed:21540187)
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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
