Mouse anti-Human/Mouse/Rat EIF4A1 Monoclonal Antibody
Mouse anti-Human/Mouse/Rat EIF4A1 Monoclonal Antibody - Image 2

Mouse anti-Human/Mouse/Rat EIF4A1 Monoclonal Antibody

Mouse anti-Human/Mouse/Rat EIF4A1 Monoclonal Antibody — ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.

SKU: BCREC-000099MA Category:
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Product Specifications

Uniprot No.P60842
Target NamesEIF4A1
Species ReactivityMouse
ImmunogenSynthetic Peptide
ConjugateNon-conjugated
IsotypeIgG
ClonalityMonoclonal
ApplicationsELISA,WB,IHC,IF
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. As a result, promotes cell proliferation and growth.

Biological Context

Subcellular Location: Cytoplasm, perinuclear region; Cell membrane; Cytoplasm, Stress granule

Product Specifications

Mouse anti-Human/Mouse/Rat EIF4A1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA,WB,IHC,IF

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome (PubMed:20156963). In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. As a result, promotes cell proliferation and growth (PubMed:20156963)

Subcellular Location

Cytoplasm, perinuclear region; Cell membrane; Cytoplasm, Stress granule

Subunit

(Microbial infection) Interacts with human cytomegalovirus/HHV-5 protein UL69

Gene: EIF4A1  |  Organism: Homo sapiens  |  Synonyms: ATP-dependent RNA helicase eIF4A-1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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