Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 2
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 3
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 4
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 5
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 6
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 7
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 8
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 9
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 10
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 11
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 12
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 13
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 14
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 15
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 16
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 17
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 18
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 19
Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody - Image 20

Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody

Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody — Binds to the myc promoter and acts as a transcriptional repressor.

SKU: BCREC-000155MA Category:
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Product Specifications

Uniprot No.P06733
Target NamesENO1
Species ReactivityMouse
ImmunogenRecombinant Human Alpha-enolase protein (2-434AA)
ConjugateNon-conjugated
IsotypeIgG1
ClonalityMonoclonal
ApplicationsELISA, WB, IHC, IF, FC, IP
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons
Pathway: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5

Product Specifications

Mouse anti-Human/Mouse/Rat/Rabbit sapiens (Human) ENO1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB, IHC, IF, FC, IP

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor

Subcellular Location

Nucleus

Tissue Specificity

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons

Subunit

Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific (PubMed:18560153). ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding (PubMed:9308760). Isoform MBP-1 interacts with TRAPPC2B (PubMed:11134351). Interacts with ENO4 and PGAM2 (By similarity). Interacts with CMTM6 (PubMed:28813417)

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5

Gene: ENO1  |  Organism: Homo sapiens  |  Synonyms: 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; Phosphopyruvate hydratase; Plasminogen-binding protein
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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