Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody
Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody - Image 2
Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody - Image 3
Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody - Image 4

Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody

Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody — Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate.

SKU: BCREC-000478MA Category:
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Product Specifications

Uniprot No.Q9UJ70
Target NamesNAGK
Species ReactivityMouse
ImmunogenRecombinant Human NAGK protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG1
ClonalityMonoclonal
ApplicationsELISA, WB, FC, ICC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has N-acetylmannosamine (ManNAc) kinase activity.

Biological Context

Tissue Specificity: Ubiquitous
Pathway: Amino-sugar metabolism; N-acetylneuraminate degradation

Product Specifications

Mouse anti-Human/Mouse sapiens (Human) NAGK Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB, FC, ICC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate (PubMed:22692205). Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (PubMed:22692205). Also has N-acetylmannosamine (ManNAc) kinase activity (By similarity). Also involved in innate immunity by promoting detection of bacterial peptidoglycan by NOD2: acts by catalyzing phosphorylation of muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, to generate 6-O-phospho-muramyl dipeptide, which acts as a direct ligand for NOD2 (PubMed:36002575)

Tissue Specificity

Ubiquitous

Subunit

Homodimer

Pathway

Amino-sugar metabolism; N-acetylneuraminate degradation

Gene: NAGK  |  Organism: Homo sapiens  |  Synonyms: GlcNAc kinase; Muramyl dipeptide kinase; N-acetyl-D-mannosamine kinase
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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