Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody
Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody - Image 2
Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody - Image 3

Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody

Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody — Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc…

SKU: BCREC-000210MA Category:
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Product Specifications

Uniprot No.P01033
Target NamesTIMP1
Species Reactivitymouse
ImmunogenHuman Timp 1
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeIgG2a
ClonalityMonoclonal
ApplicationsELISA,WB,IHC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level)

Product Specifications

Mouse anti-Human/Mouse sapiens (Human) TIMP1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA,WB,IHC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors

Subcellular Location

Secreted

Tissue Specificity

Detected in rheumatoid synovial fluid (at protein level)

Subunit

Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14. Interacts with CD63; identified in a complex with CD63 and ITGB1

Gene: TIMP1  |  Organism: Homo sapiens  |  Synonyms: Erythroid-potentiating activity; Fibroblast collagenase inhibitor; Tissue inhibitor of metalloproteinases 1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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