Mouse anti-Human sapiens (Human) AK1 Monoclonal Antibody
Mouse anti-Human sapiens (Human) AK1 Monoclonal Antibody - Image 2
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Mouse anti-Human sapiens (Human) AK1 Monoclonal Antibody

Mouse anti-Human sapiens (Human) AK1 Monoclonal Antibody — Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.

SKU: BCREC-000274MA Category:
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Product Specifications

Uniprot No.P00568
Target NamesAK1
Species ReactivityMouse
ImmunogenRecombinant Human AK1 protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG1
ClonalityMonoclonal
ApplicationsELISA, WB, FC, ICC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.

Biological Context

Subcellular Location: Cytoplasm
Disease Association: Anemia, congenital, non-spherocytic hemolytic, 3 (CNSHA3) : An autosomal recessive disease characterized by hemolytic anemia and undetectable erythrocyte adenylate kinase activity. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Mouse anti-Human sapiens (Human) AK1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) (PubMed:21080915, PubMed:23416111, PubMed:2542324). Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity)

Subcellular Location

Cytoplasm

Disease Association

Anemia, congenital, non-spherocytic hemolytic, 3 (CNSHA3) : An autosomal recessive disease characterized by hemolytic anemia and undetectable erythrocyte adenylate kinase activity. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Monomer

Gene: AK1  |  Organism: Homo sapiens  |  Synonyms: ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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