Mouse anti-Human sapiens (Human) ANXA2 Monoclonal Antibody
Mouse anti-Human sapiens (Human) ANXA2 Monoclonal Antibody - Image 2
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Mouse anti-Human sapiens (Human) ANXA2 Monoclonal Antibody

Mouse anti-Human sapiens (Human) ANXA2 Monoclonal Antibody — (Microbial infection) Binds M.

SKU: BCREC-000169MA Category:
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Product Specifications

Uniprot No.P07355
Target NamesANXA2
Species Reactivitymouse
ImmunogenRecombinant Human ANXA2 protein
ConjugateNon-conjugated
IsotypeIgG1
ClonalityMonoclonal
ApplicationsELISA,WB,IHC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

(Microbial infection) Binds M.pneumoniae CARDS toxin, probably serves as one receptor for this pathogen. When ANXA2 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane; Melanosome
Disease Association: [Increased expression of ANXA2 is associated with hepatocellular carcinoma tumor progression]

Product Specifications

Mouse anti-Human sapiens (Human) ANXA2 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA,WB,IHC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Binds M.pneumoniae CARDS toxin, probably serves as one receptor for this pathogen. When ANXA2 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen

Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane; Melanosome

Disease Association

[Increased expression of ANXA2 is associated with hepatocellular carcinoma tumor progression]

Subunit

(Microbial infection) Interacts with M.pneumoniae CARDS toxin; CARDS probably uses this protein as a receptor. A portion of internalized CARDS remains associated with intracellular annexin 2

Gene: ANXA2  |  Organism: Homo sapiens  |  Synonyms: Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; Protein I; p36
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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