Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody
Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody - Image 2
Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody - Image 3
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Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody

Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody — recombinant protein.

SKU: BCREC-000143MA Categories: ,
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Product Specifications

Uniprot No.P13987
Target NamesCD59
Species Reactivitymouse
ImmunogenRecombinant CD59 Protein
ConjugateNon-conjugated
IsotypeIgG1
ClonalityMonoclonal
ApplicationsELISA,WB,IHC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit complement membrane attack complex (MAC) assembly on cell membranes.

Biological Context

Subcellular Location: Cell membrane (Lipid-anchor, GPI-anchor); Secreted
Disease Association: Hemolytic anemia, CD59-mediated, with or without polyneuropathy (HACD59) : An autosomal recessive disorder characterized by infantile onset of chronic hemolysis and a relapsing-remitting polyneuropathy, often exacerbated by infection, and manifested as hypotonia, limb muscle weakness, and hyporeflexia. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Mouse anti-Human sapiens (Human) CD59 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA,WB,IHC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit complement membrane attack complex (MAC) assembly on cell membranes

Subcellular Location

Cell membrane (Lipid-anchor, GPI-anchor); Secreted

Disease Association

Hemolytic anemia, CD59-mediated, with or without polyneuropathy (HACD59) : An autosomal recessive disorder characterized by infantile onset of chronic hemolysis and a relapsing-remitting polyneuropathy, often exacerbated by infection, and manifested as hypotonia, limb muscle weakness, and hyporeflexia. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Interacts with T-cell surface antigen CD2

Gene: CD59  |  Organism: Homo sapiens  |  Synonyms: 1F5 antigen; 20 kDa homologous restriction factor; MAC-inhibitory protein; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; Protectin
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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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